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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPLP0
All Species:
45.76
Human Site:
T258
Identified Species:
62.92
UniProt:
P05388
Number Species:
16
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P05388
NP_000993.1
317
34274
T258
L
S
V
E
T
D
Y
T
F
P
L
A
E
K
V
Chimpanzee
Pan troglodytes
XP_001168269
317
34259
T258
L
S
V
E
T
D
Y
T
F
P
L
A
E
K
V
Rhesus Macaque
Macaca mulatta
XP_001115939
275
30225
V222
F
L
E
G
V
R
N
V
A
S
V
C
L
Q
I
Dog
Lupus familis
XP_535894
317
34269
T258
L
S
V
E
T
D
Y
T
F
P
L
A
E
K
V
Cat
Felis silvestris
Mouse
Mus musculus
P14869
317
34198
T258
L
S
V
E
T
E
Y
T
F
P
L
T
E
K
V
Rat
Rattus norvegicus
P19945
317
34197
T258
L
S
V
E
T
D
Y
T
F
P
L
A
E
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515492
264
29009
L211
L
D
I
T
E
D
T
L
H
T
R
F
L
E
G
Chicken
Gallus gallus
P47826
316
34267
T258
V
A
V
E
T
D
Y
T
F
P
L
A
E
K
V
Frog
Xenopus laevis
NP_001080134
315
34079
S258
I
A
V
E
T
D
Y
S
F
P
L
A
D
K
V
Zebra Danio
Brachydanio rerio
Q9PV90
319
34735
T261
V
T
V
E
T
D
Y
T
F
P
L
A
E
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P19889
317
34184
E258
I
A
A
T
T
E
V
E
F
K
E
A
T
T
I
Honey Bee
Apis mellifera
XP_623106
317
34396
E258
I
A
A
V
T
D
I
E
F
P
E
A
T
T
I
Nematode Worm
Caenorhab. elegans
Q93572
312
33755
S258
V
A
A
V
T
D
V
S
F
K
E
A
E
T
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
O24573
319
34486
S261
V
A
V
E
T
D
Y
S
Y
P
H
A
D
K
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04204
317
33648
S261
V
A
L
A
T
E
Y
S
F
P
Q
A
E
N
V
Baker's Yeast
Sacchar. cerevisiae
P05317
312
33748
H256
V
A
I
A
A
S
Y
H
Y
P
E
I
E
D
L
Red Bread Mold
Neurospora crassa
Q96TJ5
313
33516
S256
V
A
I
E
T
E
I
S
W
P
E
I
E
E
L
Conservation
Percent
Protein Identity:
100
96.8
86.4
99.6
N.A.
97.4
98.1
N.A.
80.4
95.2
91.4
87.4
N.A.
66.2
70.9
67.5
N.A.
Protein Similarity:
100
98.1
86.4
100
N.A.
98.4
99.3
N.A.
82.9
97.4
95.9
94.3
N.A.
80.4
82
81.3
N.A.
P-Site Identity:
100
100
0
100
N.A.
86.6
100
N.A.
13.3
86.6
73.3
86.6
N.A.
20
33.3
33.3
N.A.
P-Site Similarity:
100
100
20
100
N.A.
93.3
100
N.A.
26.6
100
100
100
N.A.
46.6
53.3
60
N.A.
Percent
Protein Identity:
N.A.
52.9
N.A.
51.7
54.8
55.2
Protein Similarity:
N.A.
69.5
N.A.
68.7
74.1
74.1
P-Site Identity:
N.A.
53.3
N.A.
46.6
20
26.6
P-Site Similarity:
N.A.
93.3
N.A.
80
53.3
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
53
18
12
6
0
0
0
6
0
0
71
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% C
% Asp:
0
6
0
0
0
65
0
0
0
0
0
0
12
6
0
% D
% Glu:
0
0
6
59
6
24
0
12
0
0
30
0
65
12
0
% E
% Phe:
6
0
0
0
0
0
0
0
71
0
0
6
0
0
0
% F
% Gly:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
6
% G
% His:
0
0
0
0
0
0
0
6
6
0
6
0
0
0
0
% H
% Ile:
18
0
18
0
0
0
12
0
0
0
0
12
0
0
30
% I
% Lys:
0
0
0
0
0
0
0
0
0
12
0
0
0
53
0
% K
% Leu:
36
6
6
0
0
0
0
6
0
0
48
0
12
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
6
0
0
0
0
0
0
6
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
77
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
6
0
0
6
0
% Q
% Arg:
0
0
0
0
0
6
0
0
0
0
6
0
0
0
0
% R
% Ser:
0
30
0
0
0
6
0
30
0
6
0
0
0
0
0
% S
% Thr:
0
6
0
12
83
0
6
42
0
6
0
6
12
18
0
% T
% Val:
42
0
53
12
6
0
12
6
0
0
6
0
0
0
53
% V
% Trp:
0
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
65
0
12
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _